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Reciprocal Changes in Vanilloid (TRPV1) and Endocannabinoid (CB1) Receptors Contribute to Visceral Hyperalgesia in the Water Avoidance Stressed Rat

BACKGROUND: Increasing evidence suggests that chronic stress plays an important role in the pathophysiology of several functional gastrointestinal disorders. We investigated whether CB1 and TRPV1 receptors are involved in stress induced visceral hyperalgesia. METHODS: Male rats were exposed to 1-hou...

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Bibliographic Details
Published in:Gut
Main Authors: Hong, Shuangsong, Fan, Jing, Kemmerer, Elyse S., Evans, Simon, Li, Ying, Wiley, John W.
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236191/
https://ncbi.nlm.nih.gov/pubmed/18936104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2008.157594
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