Establishment of a Novel Cell Line for the Enhanced Production of Recombinant Adeno-Associated Virus Vectors for Gene Therapy

Adeno-associated viral (AAV) vectors show great promise because of their excellent safety profile; however, pre-existing immune responses have necessitated the administration of high titer AAV, posing a significant challenge to the advancement of gene therapy involving AAV vectors. Recombinant AAV v...

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Vydáno v:Hum Gene Ther
Hlavní autoři: Satkunanathan, Stifani, Wheeler, Jun, Thorpe, Robin, Zhao, Yuan
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2014
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236031/
https://ncbi.nlm.nih.gov/pubmed/25072415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2014.041
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