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Mice That Produce ApoB100 Lipoproteins in the RPE Do Not Develop Drusen yet Are Still a Valuable Experimental System
PURPOSE. Mice typically produce apolipoprotein B (apoB)-48 and not apoB100. Apolipoprotein B100 accumulates in Bruch's membrane prior to basal deposit and drusen formation during the onset of AMD, raising the possibility that they are a trigger for these Bruch's membrane alterations. The p...
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| Publicado en: | Invest Ophthalmol Vis Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4235331/ https://ncbi.nlm.nih.gov/pubmed/25316721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15195 |
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