Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer

Cancer cells express an abnormal metabolism characterized by increased glucose consumption owing to genetic mutations and mitochondrial dysfunction. Previous studies indicate that unlike healthy tissues, cancer cells are unable to effectively use ketone bodies for energy. Furthermore, ketones inhibi...

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Bibliografiske detaljer
Udgivet i:Int J Cancer
Main Authors: Poff, AM, Ari, C, Arnold, P, Seyfried, TN, D’Agostino, DP
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2014
Fag:
Cancer Therapy
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235292/
https://ncbi.nlm.nih.gov/pubmed/24615175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28809
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