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Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer

Cancer cells express an abnormal metabolism characterized by increased glucose consumption owing to genetic mutations and mitochondrial dysfunction. Previous studies indicate that unlike healthy tissues, cancer cells are unable to effectively use ketone bodies for energy. Furthermore, ketones inhibi...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Poff, AM, Ari, C, Arnold, P, Seyfried, TN, D’Agostino, DP
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235292/
https://ncbi.nlm.nih.gov/pubmed/24615175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28809
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