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Early-onset dysfunction of retrosplenial cortex precedes overt amyloid plaque formation in Tg2576 mice
A mouse model of amyloid pathology was used to first examine using a cross-sectional designchanges in retrosplenial cortex activity in transgenic mice aged 5, 11, 17, and 23 months. Attention focused on: 1) overt amyloid labeled with β-amyloid((1-42)) and Congo Red staining, 2) metabolic function as...
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| Published in: | Neuroscience |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4235255/ https://ncbi.nlm.nih.gov/pubmed/21093545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.11.025 |
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