Scalable Generation of Universal Platelets from Human Induced Pluripotent Stem Cells

Human induced pluripotent stem cells (iPSCs) provide a potentially replenishable source for the production of transfusable platelets. Here, we describe a method to generate megakaryocytes (MKs) and functional platelets from iPSCs in a scalable manner under serum/feeder-free conditions. The method al...

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Pubblicato in:Stem Cell Reports
Autori principali: Feng, Qiang, Shabrani, Namrata, Thon, Jonathan N., Huo, Hongguang, Thiel, Austin, Machlus, Kellie R., Kim, Kyungho, Brooks, Julie, Li, Feng, Luo, Chenmei, Kimbrel, Erin A., Wang, Jiwu, Kim, Kwang-Soo, Italiano, Joseph, Cho, Jaehyung, Lu, Shi-Jiang, Lanza, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235139/
https://ncbi.nlm.nih.gov/pubmed/25418726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.09.010
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