Phenethyl isothiocyanate induces calcium mobilization and mitochondrial cell death pathway in cholangiocarcinoma KKU-M214 cells

BACKGROUND: Phenethyl isothiocyanate (PEITC) is a cancer chemopreventive agent from cruciferous vegetables. Cholangiocarcinoma (CCA) is a chemo-resistant cancer with very poor prognosis. We evaluated the effects of PEITC on induction of apoptotic cell death in relation to cellular glutathione (GSH)...

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Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Tusskorn, Ornanong, Senggunprai, Laddawan, Prawan, Auemduan, Kukongviriyapan, Upa, Kukongviriyapan, Veerapol
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235027/
https://ncbi.nlm.nih.gov/pubmed/24304591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-571
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