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Suppression of NAD(P)H-quinone oxidoreductase 1 enhanced the susceptibility of cholangiocarcinoma cells to chemotherapeutic agents

BACKGROUND: Cholangiocarcinoma (CCA) is highly resistant to most of the known chemotherapeutic treatments. NAD(P)H-quinone oxidoreductase 1 (NQO1) is an antioxidant/detoxifying enzyme recently recognized as an important contributor to chemoresistance in some human cancers. However, the contribution...

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Detalhes bibliográficos
Main Authors: Zeekpudsa, Ponsilp, Kukongviriyapan, Veerapol, Senggunprai, Laddawan, Sripa, Banchob, Prawan, Auemduan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922744/
https://ncbi.nlm.nih.gov/pubmed/24460787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-33-11
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