Inhibitors of protein synthesis also inhibit lysosomal proteolysis. Studies using cystinotic fibroblasts.

Cystine depleted cystinotic fibroblasts incubated in cystine-free medium accumulate lysosomal-free cystine from the degradation of cystine-containing intracellular and extracellular proteins. In this report we have used this characteristic of these cells to study lysosomal proteolysis. We find that...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Thoene, J G, Lemons, R, Boskovich, S, Borysko, K
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1985
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423496/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3973010/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111709
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