Inhibitors of protein synthesis also inhibit lysosomal proteolysis. Studies using cystinotic fibroblasts.

Cystine depleted cystinotic fibroblasts incubated in cystine-free medium accumulate lysosomal-free cystine from the degradation of cystine-containing intracellular and extracellular proteins. In this report we have used this characteristic of these cells to study lysosomal proteolysis. We find that...

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Bibliographische Detailangaben
Hauptverfasser: Thoene, J G, Lemons, R, Boskovich, S, Borysko, K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1985
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC423496/
https://ncbi.nlm.nih.gov/pubmed/3973010
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