Glycogen Synthase Kinase 3 Regulates Cell Death and Survival Signaling in Tumor Cells under Redox Stress()

Targeting tumor-specific metabolic adaptations is a promising anticancer strategy when tumor defense mechanisms are restrained. Here, we show that redox-modulating drugs including the retinoid N-(4-hydroxyphenyl)retinamide (4HPR), the synthetic triterpenoid bardoxolone (2-cyano-3,12-dioxooleana-1,9(...

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Publicat a:Neoplasia
Autors principals: Venè, Roberta, Cardinali, Barbara, Arena, Giuseppe, Ferrari, Nicoletta, Benelli, Roberto, Minghelli, Simona, Poggi, Alessandro, Noonan, Douglas M., Albini, Adriana, Tosetti, Francesca
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234881/
https://ncbi.nlm.nih.gov/pubmed/25246272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2014.07.012
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