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Synergistic Signaling of KRAS and Thyroid Hormone Receptor β Mutants Promotes Undifferentiated Thyroid Cancer through MYC Up-Regulation()()

Undifferentiated thyroid carcinoma is one of the most aggressive human cancers with frequent RAS mutations. How mutations of the RAS gene contribute to undifferentiated thyroid cancer remains largely unknown. Mice harboring a potent dominant negative mutant thyroid hormone receptor β, TRβPV (Thrb(PV...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neoplasia
Prif Awduron: Zhu, Xuguang, Zhao, Li, Park, Jeong Won, Willingham, Mark C., Cheng, Sheue-yann
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Neoplasia Press 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234871/
https://ncbi.nlm.nih.gov/pubmed/25246276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2014.08.003
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