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Cell-free expression and in meso crystallisation of an integral membrane kinase for structure determination

Membrane proteins are key elements in cell physiology and drug targeting, but getting a high-resolution structure by crystallographic means is still enormously challenging. Novel strategies are in big demand to facilitate the structure determination process that will ultimately hasten the day when s...

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Vydáno v:Cell Mol Life Sci
Hlavní autoři: Boland, Coilín, Li, Dianfan, Shah, Syed Tasadaque Ali, Haberstock, Stefan, Dötsch, Volker, Bernhard, Frank, Caffrey, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Basel 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234702/
https://ncbi.nlm.nih.gov/pubmed/25012698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-014-1655-7
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