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5-hydroxymethylcytosine: A new player in brain disorders?

5-hydroxymethylcytosine (5hmC), a novel modified cytosine, is oxidized from 5-methylcytosine (5mC) by the ten-eleven translocation (Tet) protein family. The specific distribution of 5hmC in mammalian brain and its roles in gene regulation suggest that 5hmC is important in brain development. 5hmC may...

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Bibliografiske detaljer
Udgivet i:Exp Neurol
Main Authors: Cheng, Ying, Bernstein, Alison, Chen, Dahua, Jin, Peng
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234697/
https://ncbi.nlm.nih.gov/pubmed/24845851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2014.05.008
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