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Altering 5-hydroxymethylcytosine modification impacts ischemic brain injury

Epigenetic modifications such as cytosine methylation and histone modification are linked to the pathology of ischemic brain injury. Recent research has implicated 5-hydroxymethylcytosine (5hmC), a DNA base derived from 5-methylcytosine (5mC) via oxidation by ten-eleven translocation (Tet) enzymes,...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Miao, Zhigang, He, Yuquan, Xin, Ning, Sun, Miao, Chen, Li, Lin, Li, Li, Jizhen, Kong, Jiming, Jin, Peng, Xu, Xingshun
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581609/
https://ncbi.nlm.nih.gov/pubmed/26231219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv307
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