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Altering 5-hydroxymethylcytosine modification impacts ischemic brain injury
Epigenetic modifications such as cytosine methylation and histone modification are linked to the pathology of ischemic brain injury. Recent research has implicated 5-hydroxymethylcytosine (5hmC), a DNA base derived from 5-methylcytosine (5mC) via oxidation by ten-eleven translocation (Tet) enzymes,...
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Publicado no: | Hum Mol Genet |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4581609/ https://ncbi.nlm.nih.gov/pubmed/26231219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv307 |
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