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How Does Domain Replacement Affect Fibril Formation of the Rabbit/Human Prion Proteins

BACKGROUND: It is known that in vivo human prion protein (PrP) have the tendency to form fibril deposits and are associated with infectious fatal prion diseases, while the rabbit PrP does not readily form fibrils and is unlikely to cause prion diseases. Although we have previously demonstrated that...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Yan, Xu, Huang, Jun-Jie, Zhou, Zheng, Chen, Jie, Liang, Yi
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234653/
https://ncbi.nlm.nih.gov/pubmed/25401497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113238
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