The C2238/αANP Variant Is a Negative Modulator of Both Viability and Function of Coronary Artery Smooth Muscle Cells

BACKGROUND: Abnormalities of vascular smooth muscle cells (VSMCs) contribute to development of vascular disease. Atrial natriuretic peptide (ANP) exerts important effects on VSMCs. A common ANP molecular variant (T2238C/αANP) has recently emerged as a novel vascular risk factor. OBJECTIVES: We aimed...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rubattu, Speranza, Marchitti, Simona, Bianchi, Franca, Di Castro, Sara, Stanzione, Rosita, Cotugno, Maria, Bozzao, Cristina, Sciarretta, Sebastiano, Volpe, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234641/
https://ncbi.nlm.nih.gov/pubmed/25401746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113108
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