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The Oncogenic MicroRNA Hsa-miR-155-5p Targets the Transcription Factor ELK3 and Links It to the Hypoxia Response

The molecular response to hypoxia is a critical cellular process implicated in cancer, and a target for drug development. The activity of the major player, HIF1α, is regulated at different levels by various factors, including the transcription factor ELK3. The molecular mechanisms of this intimate c...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Robertson, E. Douglas, Wasylyk, Christine, Ye, Tao, Jung, Alain C., Wasylyk, Bohdan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234625/
https://ncbi.nlm.nih.gov/pubmed/25401928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113050
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