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The Oncogenic MicroRNA Hsa-miR-155-5p Targets the Transcription Factor ELK3 and Links It to the Hypoxia Response

The molecular response to hypoxia is a critical cellular process implicated in cancer, and a target for drug development. The activity of the major player, HIF1α, is regulated at different levels by various factors, including the transcription factor ELK3. The molecular mechanisms of this intimate c...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Robertson, E. Douglas, Wasylyk, Christine, Ye, Tao, Jung, Alain C., Wasylyk, Bohdan
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234625/
https://ncbi.nlm.nih.gov/pubmed/25401928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113050
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