Modulation of CD112 by the alphaherpesvirus gD protein suppresses DNAM-1–dependent NK cell-mediated lysis of infected cells

Natural killer (NK) cells are key players in the innate response to viruses, including herpesviruses. In particular, the variety of viral strategies to modulate the recognition of certain herpesviruses witnesses the importance of NK cells in the control of this group of viruses. Still, NK evasion st...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Grauwet, Korneel, Cantoni, Claudia, Parodi, Monica, De Maria, Andrea, Devriendt, Bert, Pende, Daniela, Moretta, Lorenzo, Vitale, Massimo, Favoreel, Herman W.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234607/
https://ncbi.nlm.nih.gov/pubmed/25352670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409485111
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