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Structural basis of von Willebrand factor binding to platelet glycoprotein Ib and collagen. Effects of disulfide reduction and limited proteolysis of polymeric von Willebrand factor.

von Willebrand factor (vWF) is a large, multimeric glycoprotein that helps platelets adhere to vascular subendothelium. Although vWF binding to platelet receptors and connective tissue constituents is of fundamental importance in adhesion, there is little information regarding the nature of these vW...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Bockenstedt, P, Greenberg, J M, Handin, R I
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423458/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2936763/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112369
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