Structural basis of von Willebrand factor binding to platelet glycoprotein Ib and collagen. Effects of disulfide reduction and limited proteolysis of polymeric von Willebrand factor.

von Willebrand factor (vWF) is a large, multimeric glycoprotein that helps platelets adhere to vascular subendothelium. Although vWF binding to platelet receptors and connective tissue constituents is of fundamental importance in adhesion, there is little information regarding the nature of these vW...

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Autors principals: Bockenstedt, P, Greenberg, J M, Handin, R I
Format: Artigo
Idioma:Inglês
Publicat: 1986
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC423458/
https://ncbi.nlm.nih.gov/pubmed/2936763
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