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A circadian gene expression atlas in mammals: Implications for biology and medicine

To characterize the role of the circadian clock in mouse physiology and behavior, we used RNA-seq and DNA arrays to quantify the transcriptomes of 12 mouse organs over time. We found 43% of all protein coding genes showed circadian rhythms in transcription somewhere in the body, largely in an organ-...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhang, Ray, Lahens, Nicholas F., Ballance, Heather I., Hughes, Michael E., Hogenesch, John B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234565/
https://ncbi.nlm.nih.gov/pubmed/25349387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408886111
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