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Molecular defect in the sickle erythrocyte skeleton. Abnormal spectrin binding to sickle inside-our vesicles.

Although functional abnormalities of the sickle erythrocyte membrane skeleton have been described, there is little quantitative data on the function of the proteins that compose the skeleton. We have examined the association of spectrin, the major skeletal protein, with ankyrin, its high-affinity me...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Principais autores: Platt, O S, Falcone, J F, Lux, S E
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1985
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423435/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2578138/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111684
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