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Molecular defect in the sickle erythrocyte skeleton. Abnormal spectrin binding to sickle inside-our vesicles.

Although functional abnormalities of the sickle erythrocyte membrane skeleton have been described, there is little quantitative data on the function of the proteins that compose the skeleton. We have examined the association of spectrin, the major skeletal protein, with ankyrin, its high-affinity me...

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Pubblicato in:J Clin Invest
Autori principali: Platt, O S, Falcone, J F, Lux, S E
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1985
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423435/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2578138/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111684
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