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Structure-Based Evolution of Subtype-Selective Neurotensin Receptor Ligands

Subtype-selective agonists of the neurotensin receptor NTS2 represent a promising option for the treatment of neuropathic pain, as NTS2 is involved in the mediation of μ-opioid-independent anti-nociceptive effects. Based on the crystal structure of the subtype NTS1 and previous structure–activity re...

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Bibliografski detalji
Izdano u:ChemistryOpen
Glavni autori: Schaab, Carolin, Kling, Ralf Christian, Einsiedel, Jürgen, Hübner, Harald, Clark, Tim, Seebach, Dieter, Gmeiner, Peter
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234217/
https://ncbi.nlm.nih.gov/pubmed/25478316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201402031
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