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Application of experimentally verified transcription factor binding sites models for computational analysis of ChIP-Seq data

BACKGROUND: ChIP-Seq is widely used to detect genomic segments bound by transcription factors (TF), either directly at DNA binding sites (BSs) or indirectly via other proteins. Currently, there are many software tools implementing different approaches to identify TFBSs within ChIP-Seq peaks. However...

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Veröffentlicht in:BMC Genomics
Hauptverfasser: Levitsky, Victor G, Kulakovskiy, Ivan V, Ershov, Nikita I, Oshchepkov, Dmitry Yu, Makeev, Vsevolod J, Hodgman, T C, Merkulova, Tatyana I
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234207/
https://ncbi.nlm.nih.gov/pubmed/24472686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-80
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