Single-Tube Mutation Scanning of The Epidermal Growth Factor Receptor Gene Using Multiplex LATE-PCR and Lights-On/Lights-Off Probes

BACKGROUND: Numerous mutations in exons 18-21 of the epidermal growth factor receptor (EGFR) gene determine the response of many patients with non-small cell lung carcinoma (NSCLC) to anti-EGFR tyrosine kinase inhibitors (TKIs). This paper describes a single closed-tube assay for simultaneous mutati...

Full description

Saved in:
Bibliographic Details
Published in:J Mol Biomark Diagn
Main Authors: Tetrault, Shana M., Rice, John E., Wangh, Lawrence J., Sanchez, J. Aquiles
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234171/
https://ncbi.nlm.nih.gov/pubmed/25411647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-9929.1000175
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items