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DNMT3A and IDH mutations in acute myeloid leukemia and other myeloid malignancies: associations with prognosis and potential treatment strategies

The development of effective treatment strategies for most forms of acute myeloid leukemia (AML) has languished for the past several decades. There are a number of reasons for this, but key among them is the considerable heterogeneity of this disease and the paucity of molecular markers that can be...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Im, AP, Sehgal, AR, Carroll, MP, Smith, BD, Tefferi, A, Johnson, DE, Boyiadzis, M
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234093/
https://ncbi.nlm.nih.gov/pubmed/24699305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2014.124
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