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Enhancing AMPA to NMDA throughput as a convergent mechanism for antidepressant action

In this article, we first review current knowledge of the AMPA and NMDA glutamate receptors, their physiological properties and functions and their regulation by signaling cascades. We then discuss our hypothesis that the therapeutic effects of monoaminergic antidepressants and ketamine, an NMDA rec...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Drug Discov Today Ther Strateg
Päätekijät: Du, Jing, Machado-Vieira, Rodrigo, Maeng, Sungho, Martinowich, Keri, Manji, Husseini K., Zarate, Carlos A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234070/
https://ncbi.nlm.nih.gov/pubmed/25411578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddstr.2006.11.012
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