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Enhancing AMPA to NMDA throughput as a convergent mechanism for antidepressant action
In this article, we first review current knowledge of the AMPA and NMDA glutamate receptors, their physiological properties and functions and their regulation by signaling cascades. We then discuss our hypothesis that the therapeutic effects of monoaminergic antidepressants and ketamine, an NMDA rec...
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| Publicado no: | Drug Discov Today Ther Strateg |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4234070/ https://ncbi.nlm.nih.gov/pubmed/25411578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddstr.2006.11.012 |
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