Alpha-1-antitrypsin-Pittsburgh. A potent inhibitor of human plasma factor XIa, kallikrein, and factor XIIf.

Alpha-1-antitrypsin-Pittsburgh is a human variant that resulted from a point mutation in the plasma protease inhibitor, alpha 1-antitrypsin (358 Met----Arg). This defect in the alpha 1-antitrypsin molecule causes it to have greatly diminished anti-elastase activity but markedly increased antithrombi...

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Bibliografische gegevens
Hoofdauteurs: Scott, C F, Carrell, R W, Glaser, C B, Kueppers, F, Lewis, J H, Colman, R W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1986
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC423401/
https://ncbi.nlm.nih.gov/pubmed/3484755
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