Correlation between endogenous VWF:Ag and PK parameters and bleeding frequency in severe haemophilia A subjects during three-times-weekly prophylaxis with rFVIII-FS

Patients with severe haemophilia A experience frequent and spontaneous bleeding, causing debilitating damage to joints and decreasing quality of life. Prophylaxis with factor VIII (FVIII) reduces joint damage if initiated early. Circulating FVIII levels may be influenced by endogenous von Willebrand...

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Detalhes bibliográficos
Publicado no:Haemophilia
Main Authors: Lalezari, S, Martinowitz, U, Windyga, J, Enriquez, M M, Delesen, H, Schwartz, L, Scharrer, I
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233978/
https://ncbi.nlm.nih.gov/pubmed/24252058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/hae.12294
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