Comparative transcriptomics and metabolomics in a rhesus macaque drug administration study

We describe a multi-omic approach to understanding the effects that the anti-malarial drug pyrimethamine has on immune physiology in rhesus macaques (Macaca mulatta). Whole blood and bone marrow (BM) RNA-Seq and plasma metabolome profiles (each with over 15,000 features) have been generated for five...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Lee, Kevin J., Yin, Weiwei, Arafat, Dalia, Tang, Yan, Uppal, Karan, Tran, ViLinh, Cabrera-Mora, Monica, Lapp, Stacey, Moreno, Alberto, Meyer, Esmeralda, DeBarry, Jeremy D., Pakala, Suman, Nayak, Vishal, Kissinger, Jessica C., Jones, Dean P., Galinski, Mary, Styczynski, Mark P., Gibson, Greg
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233942/
https://ncbi.nlm.nih.gov/pubmed/25453034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2014.00054
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