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A novel algorithm for simplification of complex gene classifiers in cancer

The clinical application of complex molecular classifiers as diagnostic or prognostic tools has been limited by the time and cost needed to apply them to patients. Using an existing fifty-gene expression signature known to separate two molecular subtypes of the pediatric cancer rhabdomyosarcoma, we...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Wilson, Raphael A., Teng, Ling, Bachmeyer, Karen M., Bissonnette, Mei Lin Z., Husain, Aliya N., Parham, David M., Triche, Timothy J., Wing, Michele R., Gastier-Foster, Julie M., Barr, Frederic G., Hawkins, Douglas S., Anderson, James R., Skapek, Stephen X., Volchenboum, Samuel L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233649/
https://ncbi.nlm.nih.gov/pubmed/23913937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-0324
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