Clinical Application of Prognostic Gene Expression Signature in Fusion Gene-Negative Rhabdomyosarcoma: A Report from the Children's Oncology Group

PURPOSE: Pediatric rhabdomyosarcoma has two common histological subtypes: embryonal (ERMS) and alveolar (ARMS). PAX/FOXO1 fusion gene status is a more reliable prognostic marker than alveolar histology while fusion gene-negative (FN) ARMS patients are clinically similar to ERMS patients. A five-gene...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Hingorani, Pooja, Missiaglia, Edoardo, Shipley, Janet, Anderson, James R., Triche, Timothy J., Delorenzi, Mauro, Gastier-Foster, Julie, Wing, Michele, Hawkins, Douglas S., Skapek, Stephen X.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610152/
https://ncbi.nlm.nih.gov/pubmed/26473193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-3326
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