Crystal structure of bovine angiogenin at 1.5-A resolution.
The capacity of angiogenin (Ang) to induce blood vessel growth is critically dependent on its ribonucleolytic activity. Crystallography and mutagenesis of human Ang have previously shown that its pyrimidine binding site is obstructed by Gln-117, implying that a conformational change is a key part of...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42336/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7708754/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.7.2949 |
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