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MULTIPLE TESTING OF LOCAL MAXIMA FOR DETECTION OF PEAKS IN CHIP-SEQ DATA

A topological multiple testing approach to peak detection is proposed for the problem of detecting transcription factor binding sites in ChIP-Seq data. After kernel smoothing of the tag counts over the genome, the presence of a peak is tested at each observed local maximum, followed by multiple test...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Ann Appl Stat
Päätekijät: Schwartzman, Armin, Jaffe, Andrew, Gavrilov, Yulia, Meyer, Clifford A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233463/
https://ncbi.nlm.nih.gov/pubmed/25411587
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