GSK3β-dependent inhibition of AMPK potentiates activation of neutrophils and macrophages and enhances severity of acute lung injury

Although AMP-activated protein kinase (AMPK) is involved in regulating carbohydrate and lipid metabolism, activated AMPK also plays an anti-inflammatory role in many cell populations. However, despite the ability of AMPK activation to diminish the severity of inflammatory responses, previous studies...

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Publicado en:Am J Physiol Lung Cell Mol Physiol
Main Authors: Park, Dae Won, Jiang, Shaoning, Liu, Yanping, Siegal, Gene P., Inoki, Ken, Abraham, Edward, Zmijewski, Jaroslaw W.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233296/
https://ncbi.nlm.nih.gov/pubmed/25239914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00165.2014
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