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Elevated serotonergic signaling amplifies synaptic noise and facilitates the emergence of epileptiform network oscillations
Serotonin fibers densely innervate the cortical sheath to regulate neuronal excitability, but its role in shaping network dynamics remains undetermined. We show that serotonin provides an excitatory tone to cortical neurons in the form of spontaneous synaptic noise through 5-HT(3) receptors, which i...
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| Publicado no: | J Neurophysiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4233266/ https://ncbi.nlm.nih.gov/pubmed/25122717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00031.2014 |
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