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Ictal Epileptiform Activity Is Facilitated by Hippocampal GABA(A) Receptor-Mediated Oscillations

The cellular and network mechanisms of the transition of brief interictal discharges to prolonged seizures are a crucial issue in epilepsy. Here we used hippocampal slices exposed to ACSF containing 0 Mg(2+) to explore mechanisms for the transition to prolonged (3–42 sec) seizure-like (“ictal”) disc...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Köhling, Rüdiger, Vreugdenhil, Martin, Bracci, Enrico, Jefferys, John G. R.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772821/
https://ncbi.nlm.nih.gov/pubmed/10995826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-18-06820.2000
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