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Sphingosine kinase 1 (Sphk1) negatively regulates platelet activation and thrombus formation
Sphingosine 1-phosphate (S1P) is a powerful regulator of platelet formation. Enzymes generating S1P include sphingosine kinase 1. The present study thus explored the role of sphingosine kinase 1 in platelet formation and function. Activation-dependent platelet integrin α(IIb)β(3) activation and secr...
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| Pubblicato in: | Am J Physiol Cell Physiol |
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| Autori principali: | , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4233262/ https://ncbi.nlm.nih.gov/pubmed/25231106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00029.2014 |
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