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SA-4-1BBL and monophosphoryl lipid A constitute an efficacious combination adjuvant for cancer vaccines

Vaccines based on tumor-associated antigens (TAA) have limited therapeutic efficacy due to their weak immunogenic nature and the various immune evasion mechanisms active in advanced tumors. In an effort to overcome these limitations, we evaluated a combination of the T cell co-stimulatory molecule S...

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Dettagli Bibliografici
Pubblicato in:Cancer Res
Autori principali: Srivastava, Abhishek K., Dinc, Gunes, Sharma, Rajesh K., Yolcu, Esma S., Zhao, Hong, Shirwan, Haval
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233189/
https://ncbi.nlm.nih.gov/pubmed/25252915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1768-A
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