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SA-4-1BBL and monophosphoryl lipid A constitute an efficacious combination adjuvant for cancer vaccines
Vaccines based on tumor-associated antigens (TAA) have limited therapeutic efficacy due to their weak immunogenic nature and the various immune evasion mechanisms active in advanced tumors. In an effort to overcome these limitations, we evaluated a combination of the T cell co-stimulatory molecule S...
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| Опубликовано в: : | Cancer Res |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4233189/ https://ncbi.nlm.nih.gov/pubmed/25252915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1768-A |
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