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SA-4-1BBL and monophosphoryl lipid A constitute an efficacious combination adjuvant for cancer vaccines

Vaccines based on tumor-associated antigens (TAA) have limited therapeutic efficacy due to their weak immunogenic nature and the various immune evasion mechanisms active in advanced tumors. In an effort to overcome these limitations, we evaluated a combination of the T cell co-stimulatory molecule S...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Srivastava, Abhishek K., Dinc, Gunes, Sharma, Rajesh K., Yolcu, Esma S., Zhao, Hong, Shirwan, Haval
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233189/
https://ncbi.nlm.nih.gov/pubmed/25252915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1768-A
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