Efficacy of ABX196, a new NKT agonist, in prophylactic human vaccination

We have assessed the immune-regulatory and adjuvant activities of a synthetic glycolipid, ABX196, a novel analog of the parental compound α-GalCer. As expected, ABX196 demonstrated a measurable and significant adjuvant effect in mice and monkeys with no appreciable toxicity at the doses used to prom...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Vaccine
Prif Awduron: Tefit, Josianne Nitcheu, Crabé, Sandrine, Orlandini, Bernard, Nell, Haylene, Bendelac, Albert, Deng, Shenglou, Savage, Paul B., Teyton, Luc, Serra, Vincent
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233108/
https://ncbi.nlm.nih.gov/pubmed/25218293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.08.070
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg