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Role of protein kinases in stimulation of human polymorphonuclear leukocyte oxidative metabolism by various agonists. Differential effects of a novel protein kinase inhibitor.

Isoquinoline sulfonamides have recently been shown to exert novel inhibitory effects on mammalian protein kinases by competitively binding to the ATP substrate site (Hidaka, H., M. Inagaki, S. Kawamoto, and Y. Sasaki, 1984, Biochemistry, 23: 5036-5041). We synthesized a unique analog of the previous...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Gerard, C, McPhail, L C, Marfat, A, Stimler-Gerard, N P, Bass, D A, McCall, C E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423309/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3003155/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112302
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