Decreased leukotriene B4 synthesis in smokers' alveolar macrophages in vitro.

Recent studies have shown that alveolar macrophages (AM) are able to release leukotrienes (LTs). Since cigarette smoking inhibits the cyclooxygenase pathway of arachidonic acid metabolism in the AM, we evaluated the LT production by AM from smokers and nonsmokers. AM were obtained from 35 volunteers...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Laviolette, M, Coulombe, R, Picard, S, Braquet, P, Borgeat, P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1986
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423308/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3003154/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112301
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