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Turoctocog alfa (NovoEight®) – from design to clinical proof of concept
Turoctocog alfa (NovoEight®) is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cel...
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| Izdano u: | Eur J Haematol |
|---|---|
| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BlackWell Publishing Ltd
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4232928/ https://ncbi.nlm.nih.gov/pubmed/24797664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejh.12366 |
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