A new histone deacetylase inhibitor improves liverfibrosis in BDL rats through suppression of hepatic stellate cells

BACKGROUND AND PURPOSE: Activation of hepatic stellate cells (HSCs) is a crucial step in the pathogenesis of hepatic fibrosis. Histone deacetylase (HDAC) is an attractive target in liver fibrosis because it plays a key role in gene expression and cell differentiation. We have developed a HDAC inhibi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Br J Pharmacol
Hauptverfasser: Park, Ki Cheong, Park, Ji Hyun, Jeon, Jeong Yong, Kim, Sang Yong, Kim, Jung Min, Lim, Chang Yong, Lee, Tae Hyung, Kim, Hyung Kwan, Lee, Hyun Gyu, Kim, Sung Min, Kwon, Ho Jeong, Suh, Jin Suck, Kim, Seung Won, Choi, Seung Hoon
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2014
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232907/
https://ncbi.nlm.nih.gov/pubmed/24467283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12590
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge