A new histone deacetylase inhibitor improves liverfibrosis in BDL rats through suppression of hepatic stellate cells

BACKGROUND AND PURPOSE: Activation of hepatic stellate cells (HSCs) is a crucial step in the pathogenesis of hepatic fibrosis. Histone deacetylase (HDAC) is an attractive target in liver fibrosis because it plays a key role in gene expression and cell differentiation. We have developed a HDAC inhibi...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Br J Pharmacol
Main Authors: Park, Ki Cheong, Park, Ji Hyun, Jeon, Jeong Yong, Kim, Sang Yong, Kim, Jung Min, Lim, Chang Yong, Lee, Tae Hyung, Kim, Hyung Kwan, Lee, Hyun Gyu, Kim, Sung Min, Kwon, Ho Jeong, Suh, Jin Suck, Kim, Seung Won, Choi, Seung Hoon
Formáid: Artigo
Teanga:Inglês
Foilsithe: BlackWell Publishing Ltd 2014
Ábhair:
Research Papers
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232907/
https://ncbi.nlm.nih.gov/pubmed/24467283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12590
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla