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Differences in signaling pathways by IL-1β and IL-18

IL-1 and IL-18 are members of the IL-1 family of ligands, and their receptors are members of the IL-1 receptor family. Although several biological properties overlap for these cytokines, differences exist. IL-18 uniquely induces IFN-γ from T lymphocytes and natural killer cells but does not cause fe...

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Main Authors: Lee, Jae-Kwon, Kim, Soo-Hyun, Lewis, Eli C., Azam, Tania, Reznikov, Leonid L., Dinarello, Charles A.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC423278/
https://ncbi.nlm.nih.gov/pubmed/15161979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402800101
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